PD Dr. med. Igor Yakushev

Oberarzt, Leiter der Neurobildgebung

E-Mail: Igor.Yakushev@mri.tum.de(link sends e-mail)

Functions

Senior Physician, Head of Neuroimaging



Clinical works

  • Covering the whole spectrum of diagnostic and therapeutic Nuclear Medicine
  • Dedicated supervision of PET and scintigraphy examinations of the brain: 18F-FDG, 18F-FET, 68Ga-Dotanoc, 18F-labeled amyloid tracers, 11C-PIB, 18F-AV-1451, PET, DaTSCAN
  • Qualified reader of CT and X-ray images
  • Interdisciplinary boards: neuropsychiatry, neurooncology; thorax- and hematooncology

Research

  • Head of the research group “Multimodal imaging of normal and pathological cognition”
  • Coordination of the neurooncologic research
  • Clinical Investigator: Supervision of clinical trials with anti-amyloid and -tau therapeutics

Teaching

  • Seminars und lecture “Nuclear medicine diagnostics of the central nervous system“
  • Three days’ practical seminar “Interdisciplinary diagnosis of dementia”
  • Lecture „Nuclear Medicine: clinical applications“ for students of informatics
  • Seminar „PET in Neuro-oncology“ for students of technical specialities

Cover letter

Professional history


2008-2011Resident, Dept. of Psychiatry and Psychotherapy (Prof. K. Lieb), University Hospital Mainz, Germany. Research group “Normal Aging” (Prof. A. Fellgiebel)
2011-2011Rotating Physician, Dept. of Neurology (Prof. F. Zipp), University Hospital Mainz, Germany
Since 2012Dept. of Nuclear Medicine (since 2/2018 Prof. W. Weber, before Prof. M. Schwaiger), Technical University of Munich,  Germany
2012-2016Resident
          2013Head, research group “Multimodal imaging of normal and pathological cognition”
          2015Head of Neuroimaging
          2017Specialist in Nuclear Medicine
          2017        Coordinator of the neurooncologic research
          2018Senior Physician
          2020Assistant Professor (Habilitation), Assessment of metabolic connectivity by means of PET (Prof. M. Schwaiger)
          2021

Qualified reader of X-ray and CT images

  

Education

 
1998-2004Studies of Human Medicine at the Northern State Medical University, Archangelsk, Russia
WS 2003/04Medicine courses at the University of Oulu, Finland, as scholar of the Center of International Mobility (CIMO), Finland
06/2004Final state examination with distinction (overall score of 1.1 out of 1.0)
2004-2006Doctoral studies as scholar of the German Research Foundation (DFG) at the Neuro-Graduate School and Dept. of Nuclear Medicine, University of Mainz, Germany
2006-2007Practical year (pre-registration) at the University Hospital Mainz, Germany
10/2007          Final state examination, University of Mainz, Germany
05/2010M.D. thesis “In vivo imaging of dopamine receptors in temporal lobe epilepsy”, Dept. of Nuclear Medicine (Prof. P. Bartenstein), University of Mainz (magna cum laude)

Further functions


  • Since 2015   Head of Neuroimaging, Dominantly Inherited Alzheimer Network (DIAN) Munich
  • 2017 - 2019  Leadership Board of young professionals, German Society of Nuclear Medicine
  • Since 2017   Faculty, PhD Program “Medical Life Science and Technology”, TUM
  • Since 2018   Associate Faculty, Munich Center for NeuroSciences - Brain and Mind
  • Since 2019   Working Group “Neuro-Nuclear-Medicine”, German Society of Nuclear Medicine
  • 2019 - 2020  Board of Directors, Brain Imaging Council, Society of Nuclear Medicine and Molecular Imaging
  • Since 2022   Member, European DLB Consortium
  • Since 2022   Head, Molecular Connectivity Working Group www.molecularconnectivity.com
  • Since 2023   Neuroimaging Committee, European Association of Nuclear Medicine

Reviewer

  • Journals: Alzheimer’s & Dementia, American Journal of Neuroradiology, Brain Imaging and Behavior, Brain Structure and Function, Cerebral Cortex, Clinical Neuroradiology, Cortex, Current Alzheimer Research, Dementia and Geriatric Cognitive Disorders, Epilepsia, European Journal of Nuclear Medicine and Molecular Imaging, EJNMMI Research, Frontiers Aging Neuroscience, Human Brain Mapping, International Journal of Alzheimer’s Disease, IEEE Journal of Biomedical and Health Informatics, Journal of Cerebral Blood Flow and Metabolism, Journal of Nuclear Medicine, Journal of Psychiatry and Neuroscience, Molecular Psychiatry, Nature Communications, Nature Protocols, Neurobiology of Aging, Neuroimage, Psychiatry Research Neuroimaging, Theranostics
  • Funding Institutions: FWF Austrian Science Fund, Alzheimer's Research UK, German Academic Scholarship Foundation
  • Conferences: Annual meetings of the German Society of Nuclear Medicine, Society of Nuclear Medicine and Molecular Imaging

Editorial Boards: Frontiers in Medicine (Associate Editor)


Grant Support (as Principle Investigator)


  • 2012-2013    Intramural TUM grant for resident physicians, “Identification of Alzheimer-typical  covariance patterns in amyloid imaging data“. 
  • 2013-2015    Alzheimer Research Initiative (AFI) Germany, “Brain β-Amyloid signature of Alzheimer’s disease”. 
  • 2013-2018    7th EU Framework Programme for Research, technological Development and Demonstration, “Multimodal Imaging of Neurological Disorders”. Applicant (PI: Prof. Schwaiger).
  • 2016-2019    German Research Foundation (DFG), “Plasticity of large-scale neural connectivity following working memory training”. 
  • 2020-2022    Federal Ministry of Education and Research Germany (BMBF), “Deep learning for the differential diagnosis of dementia from multi-modal neuroimaging data”. 
  • 2021-2024    German Research Foundation (DFG), “Striatal dopamine in psychosis and psychotic remission and its relevance for cognitive difficulties in schizophrenia: a longitudinal 18F-DOPA-PET/fMRI hybrid imaging study”.

Publications 

(state Dec. 2022)


Articles in peer reviewed journals: 101

  • As first or senior author:           32
  • H-Index (google scholar):         32
  • Cites (google scholar):              > 3000

Book chapters: 2