PD Dr. med. Igor Yakushev

Oberarzt, Leiter der Neurobildgebung

E-Mail: Igor.Yakushev@mri.tum.de(link sends e-mail)

Functions

Senior Physician, Head of Neuroimaging

Clinical works

  • Covering the whole spectrum of diagnostic and therapeutic Nuclear Medicine
  • Dedicated supervision of PET and scintigraphy examinations of the brain: 18F-FDG, 18F-FET, 68Ga-Dotanoc, 18F-labeled amyloid tracers, 11C-PIB, 18F-AV-1451, PET, DaTSCAN
  • Qualified reader of CT and X-ray images
  • Interdisciplinary boards: neuropsychiatry, neurooncology; thorax- and hematooncology

Research

  • Head of the research group “Multimodal imaging of normal and pathological cognition”
  • Coordination of the neurooncologic research
  • Supervision of clinical trials with anti-amyloid and -tau therapeutics
  • Head of neuroimaging, Dominantly Inherited Alzheimer Network (DIAN) Munich

Teaching

  • Seminars und lecture “Nuclear medicine diagnostics of the central nervous system“
  • Facultative 3 days’ practical seminar “Interdisciplinary diagnosis of dementia”

Cover letter

Professional history

 
2008-2011 Resident, Dept. of Psychiatry and Psychotherapy (Prof. K. Lieb), University Hospital Mainz, Germany. Research group “Normal Aging” (Prof. A. Fellgiebel)
2011-2011 Rotating Physician, Dept. of Neurology (Prof. F. Zipp), University Hospital Mainz, Germany
Since 2012 Dept. of Nuclear Medicine (since 2/2018 Prof. W. Weber, before Prof. M. Schwaiger), Technical University of Munich,  Germany
2012-2016 Resident
          2013 Head, research group “Multimodal imaging of normal and pathological cognition”
          2015 Head of Neuroimaging
          2017 Specialist in Nuclear Medicine
          2017         Coordinator of the neurooncologic research
          2018 Senior Physician
          2020 Assistant Professor (Habilitation), Assessment of metabolic connectivity by means of PET (Prof. M. Schwaiger)
          2021

Qualified reader of X-ray and CT images

  

Education

 
1998-2004 Studies of Human Medicine at the Northern State Medical University, Archangelsk, Russia
WS 2003/04 Medicine courses at the University of Oulu, Finland, as scholar of the Center of International Mobility (CIMO), Finland
06/2004 Final state examination with distinction (overall score of 1.1 out of 1.0)
2004-2006 Doctoral studies as scholar of the German Research Foundation (DFG) at the Neuro-Graduate School and Dept. of Nuclear Medicine, University of Mainz, Germany
2006-2007 Practical year (pre-registration) at the University Hospital Mainz, Germany
10/2007           Final state examination, University of Mainz, Germany
05/2010 M.D. thesis “In vivo imaging of dopamine receptors in temporal lobe epilepsy”, Dept. of Nuclear Medicine (Prof. P. Bartenstein), University of Mainz (magna cum laude)

Further functions

  • Since 2016   Associate Faculty, Munich Center for NeuroSciences - Brain and Mind
  • Since 2017   Faculty, PhD Program “Medical Life Science and Technology”, TUM
  • Since 2017   Leadership board of young professionals, German Society of Nuclear Medicine
  • Since 2018   Working Group “Neuro-Nuclear-Medicine”, German Society of Nuclear Medicine     
  • 2018 - 2019  Board of Directors, Brain Imaging Council, Society of Nuclear Medicine and Molecular Imaging

Reviewer

  • Journals: Alzheimer’s & Dementia, American Journal of Neuroradiology, Brain Imaging and Behavior, Brain Structure and Function, Cerebral Cortex, Clinical Neuroradiology, Cortex, Current Alzheimer Research, Dementia and Geriatric Cognitive Disorders, Epilepsia, European Journal of Nuclear Medicine and Molecular Imaging, EJNMMI Research, Frontiers Aging Neuroscience, Human Brain Mapping, International Journal of Alzheimer’s Disease, Journal of Cerebral Blood Flow and Metabolism, Journal of Nuclear Medicine, Journal of Psychiatry and Neuroscience, Molecular Psychiatry, Nature Protocols, Neurobiology of Aging, Neuroimage, Psychiatry Research Neuroimaging, Theranostics
  • Funding Institutions: FWF Austrian Science Fund, Alzheimer's Research UK, German Academic Scholarship Foundation
  • Conferences: Annual meetings of the German Society of Nuclear Medicine, Society of Nuclear Medicine and Molecular Imaging

Editorial Boards: Frontiers in Medicine (Associate Editor)

Grant Support (as Principle Investigator)

  • 2012-2013    Intramural TUM grant for resident physicians, “Identification of Alzheimer-typical  covariance patterns in amyloid imaging data“. 
  • 2013-2015    Alzheimer Research Initiative (AFI) Germany, “Brain β-Amyloid signature of Alzheimer’s disease”. 
  • 2013-2018    7th EU Framework Programme for Research, technological Development and Demonstration, “Multimodal Imaging of Neurological Disorders”. Applicant (PI: Prof. Schwaiger).
  • 2016-2019    German Research Foundation (DFG), “Plasticity of large-scale neural connectivity following working memory training”. 
  • 2020-2022    Federal Ministry of Education and Research Germany (BMBF), “Deep learning for the differential diagnosis of dementia from multi-modal neuroimaging data”. 
  • 2021-2024    German Research Foundation (DFG), “Striatal dopamine in psychosis and psychotic remission and its relevance for cognitive difficulties in schizophrenia: a longitudinal 18F-DOPA-PET/fMRI hybrid imaging study”.

Publications 

(state Dec. 2021)

Articles in peer reviewed journals: 85

  • As first or senior author:           29
  • H-Index (google scholar):         32
  • Cites (google scholar):              > 2600

Book chapters: 2